The PCAF antibody from MyBioSource.com is a Rabbit Polyclonal antibody to Caf, KAT2B, P/CAF, and PCAF. This antibody recognizes Human antigen. The PCAF antibody has been validated for the following applications: Western Blot.
Description
CBP and p300 are large nuclear proteins that bind to many sequence-specific factors involved in cell growth and/or differentiation, including c-jun and the adenoviral oncoprotein E1A. The protein encoded by this gene associates with p300/CBP. It has in vitro and in vivo binding activity with CBP and p300, and competes with E1A for binding sites in p300/CBP. It has histone acetyl transferase activity with core histones and nucleosome core particles, indicating that this protein plays a direct role in transcriptional regulation. [provided by RefSeq]